Non-Invasive Prenatal Testing Market

Industry Overview

The Global Non-Invasive Prenatal Testing (NIPT) Market was valued at USD 2.8 billion in 2023 and is anticipated to reach USD 6.83 billion by 2030, witnessing a CAGR of 12.35% during 2025-2030. Non-invasive prenatal testing (NIPT) is a sensitive diagnostic method for identifying specific chromosomal abnormalities in the developing fetus. Chromosomal disorders such as Turner syndrome, Edwards syndrome, Patau syndrome, and down syndrome are some of the diseases which are screened using NIPT. The global non-invasive prenatal testing market is growing at a significant rate, due to mounting occurrence of chromosomal abnormalities, mounting maternal age and introduction of advanced products. Different products contributed to the non-invasive prenatal testing market size. The market has witnessed a high demand for consumables over the last few years due to repeated supplies of consumables as compared to instruments. The non-invasive prenatal testing (NIPT) market is a rapidly growing sector within the field of prenatal diagnostics. NIPT is a screening test that analyzes fetal DNA in the maternal blood to detect genetic abnormalities in the fetus. It offers a safer and more accurate alternative to traditional invasive procedures such as amniocentesis or chorionic villus sampling (CVS). The NIPT market has experienced significant growth in recent years due to several factors. First, advancements in technology, particularly in DNA sequencing and bioinformatics, have made it possible to detect fetal chromosomal abnormalities with high sensitivity and specificity. This has increased the reliability and accuracy of NIPT, making it a preferred choice for prenatal screening.

Market Segmentation

Insight by Product

On the basis of product, the market is subdivided into instruments and consumables. Repeated supplies of consumables are the factors responsible for the growth of the consumables segment. Of both the products, the consumables account the foremost share in the non-invasive prenatal testing market. The instruments market is further subdivided into next-generation sequencing systems, microarrays, ultrasound devices, polymerase chain reaction instruments, and others. In addition, consumables are further subdivided into disposables and assay kits & reagents

Insight by Method

On the basis of method, the market is subdivided into cell-free DNA in maternal plasma tests, ultrasound detection, fetal cell in maternal blood tests, and biochemical screening tests. Mounting need for cell free-DNA based techniques and expanding government schemes to offer prenatal services are the factors growing the demand for cell-free DNA in maternal plasma tests. Among all methods, the cell-free DNA in maternal plasma tests is expected to grow at the fastest rate in the non-invasive prenatal testing market. In addition, ultrasound detection segment accounted for the largest share in the market.

Insight by Application

On the basis of application, the market is subdivided into microdeletion syndrome, trisomy, and others. Increasing occurrence of chromosomal abnormalities with mounting maternal age is the factor responsible for the growth of the trisomy segment. Of all the applications, the trisomy accounted for the largest share and is expected to grow at the fastest rate in the non-invasive prenatal testing market.

Insight by End User

On the basis of end-user, the market is subdivided into hospitals and diagnostic laboratories. Mounting occurrence of chromosomal abnormalities and mounting schemes by companies to provide advanced products to diagnostic laboratories are some of the factors responsible for the growth of the diagnostic laboratories segment. Of both end-users, the diagnostic laboratories accounted for the largest share in the non-invasive prenatal testing market.

Global Non-Invasive Prenatal Testing Market Report Coverage

Industry Dynamics

Growth Drivers

The refining reimbursement scenario for NIPT, mounting occurrence of chromosomal abnormalities, Mounting average maternal age, and introduction of advanced products are the primary growth drivers for the non-invasive prenatal testing market. For instance, according to the World Health Organization (WHO), each year approximately 3,000 to 5,000 children are born with a chromosome disorder.

Budding inclination for non-invasive techniques, mounting healthcare expenditure and programs focusing on boosting the alertness of NIPT are also facilitating the growth for the non-invasive prenatal testing market.

The market for NIPT has been growing rapidly in recent years due to several factors. These include increasing maternal age, rising awareness and acceptance of genetic testing, advancements in technology, and the availability of a broader range of testing options. Additionally, the declining cost of genetic sequencing has made NIPT more accessible to a larger population.

Challenges

The absence of skilled professionals and the consistency of test results in obese are the major challenges to the growth of non-invasive prenatal testing market. In addition, the ethical hurdle is also hindering the growth of the market. Social-cultural values and norms, misuse of NIPT for minor conditions, accessibility and affordability, justice, and fairness, permissibly legalizing termination of pregnancy due to a disability or any other undesired conditions, and others are some of the concerns associated with NIPT.

Industry Ecosystem

Globally, manufacturing companies trying to enter the non-invasive prenatal testing market are required to maintain stringent regulatory standards. Moreover, the high level of capital requirement also poses a major barrier to the entry of new players.

Increasing adoption: NIPT has gained widespread acceptance among pregnant women and healthcare professionals due to its high accuracy, low risk, and early detection capabilities.

Advancements in technology: The development of next-generation sequencing (NGS) and other advanced molecular techniques has greatly improved the accuracy and reliability of NIPT, leading to increased demand.

Rising maternal age: Advanced maternal age is associated with a higher risk of chromosomal abnormalities in fetuses. As women delay childbearing, there is a growing need for effective prenatal screening methods, further fueling the demand for NIPT.

Expanded applications: NIPT has expanded beyond detecting common chromosomal abnormalities to include screening for other genetic disorders and conditions, such as certain single-gene disorders and fetal aneuploidies.

Increasing awareness: Public awareness campaigns, educational initiatives, and improved accessibility to NIPT services have contributed to the market's growth by informing expectant parents about the benefits of non-invasive testing.

Geographic Overview

Geographically, North America is the largest non-invasive prenatal testing market as in the region the occurrence of chromosomal abnormalities is increasing. Mounting maternal age, improved healthcare infrastructure, and boosting alertness programs are also surging the growth of the North American non-invasive prenatal testing market. For instance, according to the Centre for Disease Control and Prevention (CDC) report on National Vital Statistics Report 2015, in the U.S., the mean age of a mother at first birth was 25.8 years in 2012, and it increased to 26 years in 2013.

Asia-Pacific is observed to witness the fastest growth in the market, due to mounting healthcare expenditure. In addition, boosting alertness programs and conferences is also creating a positive impact on the Non-invasive prenatal testing market growth in the region.

Competitive Insight

Key players in the non-invasive prenatal testing market are catering to the demand for these devices by investing in technologically advanced products in their product portfolio across the globe. In December 2017, PerkinElmer, Inc. acquired EUROIMMUN Medical Laboratory Diagnostics AG, to strengthen its position in China and other emerging countries. GE Healthcare, Perkinelmer, Inc., Koninklijke N.V., Qiagen, Pacific Biosciences of California, Inc., Agilent Technologies, Inc., and Beijing Genomics Institute are the key players offering non-invasive prenatal testing.

Pacific Biosciences of California, Inc., has acquired Omniome, to expand its market opportunities for sequencing innovative ways and add value to customers. Omniome has a novel approach to having an accurate short-read sequencing platform and entering large, fast-growing clinical applications such as oncology and non-invasive prenatal testing.

The Non-Invasive Prenatal Testing Market report offers a comprehensive market segmentation analysis along with an estimation for the forecast period 2025–2030.

Segments Covered in the Report

• By Product
  • Instruments
  • Consumables
• By Method
  • Cell- Free DNA in Maternal Plasma Tests
  • Ultrasound Detection
  • Fetal Cell in Maternal Blood Tests
  • Biochemical Screening Tests
• By Application
  • Microdeletion Syndrome
  • Trisomy
  • Others
• By End User
  • Hospitals
  • Diagnostic Laboratories

Region Covered in the Report

• North America
  • U.S.
  • Canada
  • Mexico
• Europe
  • Germany
  • U.K.
  • France
  • Italy
  • Spain
  • Russia
  • Rest of Europe
• Asia-Pacific (APAC)
  • China
  • Japan
  • India
  • South Korea
  • Rest of Asia-Pacific
• Rest of the World (RoW)
  • Brazil
  • Saudi Arabia
  • South Africa
  • U.A.E.
  • Other Countries

Source: VynZ Research

1.    Research Overview

        1.1.    The Report Offers
        1.2.    Market Coverage
                1.2.1.    By Product
                1.2.2.    By Method
                1.2.3.    By Application
                1.2.4.    By End User              
                1.2.5.    By Region
        1.3.    Research Phases
        1.4.    Limitations
        1.5.    Market Methodology
                1.5.1.    Data Sources
                        1.5.1.1. Primary Research
                        1.5.1.2. Secondary Research
                1.5.2.    Methodology
                        1.5.2.1. Data Exploration
                        1.5.2.2. Forecast Parameters
                        1.5.2.3. Data Validation
                        1.5.2.4. Assumptions
                1.5.3.    Study Period & Data Reporting Unit

2.    Executive Summary

3.    Industry Overview

        3.1.    Industry Dynamics
                3.1.1.    Market Growth Drivers
                3.1.2.    Market Restraints
                3.1.3.    Key Market Trends
                3.1.4.    Major Opportunities
        3.2.    Industry Ecosystem
                3.2.1.    Porter’s Five Forces Analysis
                3.2.2.    Recent Development Analysis
                3.2.3.    Value Chain Analysis
        3.3.    Competitive Insight
                3.3.1.    Competitive Position of Industry Players
                3.3.2.    Market Attractive Analysis
                3.3.3.    Market Share Analysis

4.    Global Market Estimate and Forecast

        4.1.    Global Market Overview
        4.2.    Global Market Estimate and Forecast to 2030

5.    Market Segmentation Estimate and Forecast

        5.1.    By Product
                5.1.1.    Instruments
                        5.1.1.1. Market Definition
                        5.1.1.2. Market Estimation and Forecast to 2030
                5.1.2.    Consumables
                        5.1.2.1. Market Definition
                        5.1.2.2. Market Estimation and Forecast to 2030
        5.2.    By Method
                5.2.1. Cell-Free DNA in Maternal Plasma Tests
                        5.2.1.1. Market Definition
                        5.2.1.2. Market Estimation and Forecast to 2030
                5.2.2.    Ultrasound Detection
                        5.2.2.1. Market Definition
                        5.2.2.2. Market Estimation and Forecast to 2030
                5.2.3.    Fetal Cell in Maternal Blood Tests
                        5.2.2.1. Market Definition
                        5.2.2.2. Market Estimation and Forecast to 2030
                5.2.3.    Biochemical Screening Tests
                        5.2.2.1. Market Definition
                        5.2.2.2. Market Estimation and Forecast to 2030
        5.3.   By Application 
                5.3.1.    Microdeletion Syndrome
                        5.3.1.1. Market Definition
                        5.3.1.2. Market Estimation and Forecast to 2030
                5.3.2.    Trisomy
                        5.3.2.1. Market Definition
                        5.3.2.2. Market Estimation and Forecast to 2030
                5.3.3.    Others
                        5.3.3.1. Market Definition
                        5.3.3.2. Market Estimation and Forecast to 2030
5.3.    By End User 
                5.3.1.    Hospitals
                        5.3.1.1. Market Definition
                        5.3.1.2. Market Estimation and Forecast to 2030
                5.3.2.    Diagnostic Laboratories
                        5.3.2.1. Market Definition
                        5.3.2.2. Market Estimation and Forecast to 2030
        
6.    North America Market Estimate and Forecast

        6.1.    By Product
        6.2.    By Method
        6.3.    By Application       
        6.4.    By End User
        6.5.    By Country – Germany, U.K., France, Italy, Spain, Russia, and Rest of Europe
                6.5.1.    U.S. Market Estimate and Forecast
                6.5.2.    Canada Market Estimate and Forecast
                6.5.3.    Mexico Market Estimate and Forecast

7.    Europe Market Estimate and Forecast

        7.1.    By Product
        7.2.    By Method
        7.3.    By Application       
        7.4.    By End User
        7.5.    By Country – Germany, U.K., France, Italy, Spain, Russia, and Rest of Europe
                7.5.1.    Germany Market Estimate and Forecast
                7.5.2.    France Market Estimate and Forecast
                7.5.3.    U.K. Market Estimate and Forecast
                7.5.4.    Italy Market Estimate and Forecast
                7.5.5.    Spain Market Estimate and Forecast
                7.5.6.    Rest of Europe Market Estimate and Forecast

8.    Asia-Pacific Market Estimate and Forecast

        8.1.    By Product
        8.2.    By Method
        8.3.    By Application       
        8.4.    By End User
        8.5.    By Country – Germany, U.K., France, Italy, Spain, Russia, and Rest of Europe
                8.5.1.    China Market Estimate and Forecast
                8.5.2.    Japan Market Estimate and Forecast
                8.5.3.    India Market Estimate and Forecast
                8.5.4.    South Korea Market Estimate and Forecast
                8.5.5.    Singapore Market Estimate and Forecast
                8.5.6.    Rest of Asia-Pacific Market Estimate and Forecast

9.    Rest of the World (RoW) Market Estimate and Forecast

        9.1.    By Product
        9.2.    By Method
        9.3.    By Application       
        9.4.    By End User
        9.5.    By Country – Germany, U.K., France, Italy, Spain, Russia, and Rest of Europe
                9.5.1.    Brazil Market Estimate and Forecast
                9.5.2.    Saudi Arabia Market Estimate and Forecast
                9.5.3.    South Africa Market Estimate and Forecast
                9.5.4.    Other Countries Market Estimate and Forecast

10.    Company Profiles

        10.1.    GE Healthcare
                10.1.1.    Snapshot
                10.1.2.    Overview
                10.1.3.    Offerings
                10.1.4.    Financial Insight
                10.1.5.    Recent Developments
        10.2.    Perkinelmer Inc.
                10.2.1.    Snapshot
                10.2.2.    Overview
                10.2.3.    Offerings
                10.2.4.    Financial Insight
                10.2.5.    Recent Developments
        10.3.    Koninklijke N.V.
                10.3.1.    Snapshot
                10.3.2.    Overview
                10.3.3.    Offerings
                10.3.4.    Financial Insight
                10.3.5.    Recent Developments
        10.4.    Qiagen
                10.4.1.    Snapshot
                10.4.2.    Overview
                10.4.3.    Offerings
                10.4.4.    Financial Insight
                10.4.5.    Recent Developments
        10.5.    Pacific Biosciences of California Inc.
                10.5.1.    Snapshot
                10.5.2.    Overview
                10.5.3.    Offerings
                10.5.4.    Financial Insight
                10.5.5.    Recent Developments
        10.6.    Agilent Technologies Inc.
                10.6.1.    Snapshot
                10.6.2.    Overview
                10.6.3.    Offerings
                10.6.4.    Financial Insight
                10.6.5.    Recent Developments
        10.7.    Beijing Genomics Institute
                10.7.1.    Snapshot
                10.7.2.    Overview
                10.7.3.    Offerings
                10.7.4.    Financial Insight
                10.7.5.    Recent Developments   

11.    Appendix

        11.1.    Exchange Rates
        11.2.    Abbreviations

Note: Financial insight and recent developments of different companies are subject to the availability of information in the secondary domain.

List of Tables

Table 1 Sources
Table 2 Study Periods
Table 3 Data Reporting Unit
Table 4 Global Non-Invasive Prenatal Testing Market, By Product, 2018 - 2023 (USD Billion)
Table 5 Global Non-Invasive Prenatal Testing Market, By Product, 2025 - 2030 (USD Billion)
Table 6 Global Non-Invasive Prenatal Testing Market, By Method, 2018 - 2023 (USD Billion)
Table 7 Global Non-Invasive Prenatal Testing Market, By Method, 2025 - 2030 (USD Billion)
Table 8 Global Non-Invasive Prenatal Testing Market, By Application, 2018 - 2023 (USD Billion)
Table 9 Global Non-Invasive Prenatal Testing Market, By Application, 2025 - 2030 (USD Billion)
Table 10 Global Non-Invasive Prenatal Testing Market, By End User, 2018 - 2023 (USD Billion)
Table 11 Global Non-Invasive Prenatal Testing Market, By End User, 2025 - 2030 (USD Billion)
Table 12 Global Non-Invasive Prenatal Testing Market, By Region, 2018 - 2023 (USD Billion)
Table 13 Global Non-Invasive Prenatal Testing Market, By Region, 2025 - 2030 (USD Billion)
Table 14 North America Non-Invasive Prenatal Testing Market, By Product, 2018 - 2023 (USD Billion)
Table 15 North America Non-Invasive Prenatal Testing Market, By Product, 2025 - 2030 (USD Billion)
Table 16 North America Non-Invasive Prenatal Testing Market, By Method, 2018 - 2023 (USD Billion)
Table 17 North America Non-Invasive Prenatal Testing Market, By Method, 2025 - 2030 (USD Billion)
Table 18 North America Non-Invasive Prenatal Testing Market, By Application, 2018 - 2023 (USD Billion)
Table 19 North America Non-Invasive Prenatal Testing Market, By Application, 2025 - 2030 (USD Billion)
Table 20 North America Non-Invasive Prenatal Testing Market, By End User, 2018 - 2023 (USD Billion)
Table 21 North America Non-Invasive Prenatal Testing Market, By End User, 2025 - 2030 (USD Billion)
Table 22 North America Non-Invasive Prenatal Testing Market, By Region, 2018 - 2023 (USD Billion)
Table 23 North America Non-Invasive Prenatal Testing Market, By Region, 2025 - 2030 (USD Billion)
Table 24 Europe Non-Invasive Prenatal Testing Market, By Product, 2018 - 2023 (USD Billion)
Table 25 Europe Non-Invasive Prenatal Testing Market, By Product, 2025 - 2030 (USD Billion)
Table 26 Europe Non-Invasive Prenatal Testing Market, By Method, 2018 - 2023 (USD Billion)
Table 27 Europe Non-Invasive Prenatal Testing Market, By Method, 2025 - 2030 (USD Billion)
Table 28 Europe Non-Invasive Prenatal Testing Market, By Application, 2018 - 2023 (USD Billion)
Table 29 Europe Non-Invasive Prenatal Testing Market, By Application, 2025 - 2030 (USD Billion)
Table 30 Europe Non-Invasive Prenatal Testing Market, By End User, 2018 - 2023 (USD Billion)
Table 31 Europe Non-Invasive Prenatal Testing Market, By End User, 2025 - 2030 (USD Billion)
Table 32 Europe Non-Invasive Prenatal Testing Market, By Region, 2018 - 2023 (USD Billion)
Table 33 Europe Non-Invasive Prenatal Testing Market, By Region, 2025 - 2030 (USD Billion)
Table 34 Asia-Pacific Non-Invasive Prenatal Testing Market, By Product, 2018 - 2023 (USD Billion)
Table 35 Asia-Pacific Non-Invasive Prenatal Testing Market, By Product, 2025 - 2030 (USD Billion)
Table 36 Asia-Pacific Non-Invasive Prenatal Testing Market, By Method, 2018 - 2023 (USD Billion)
Table 37 Asia-Pacific Non-Invasive Prenatal Testing Market, By Method, 2025 - 2030 (USD Billion)
Table 38 Asia-Pacific Non-Invasive Prenatal Testing Market, By Application, 2018 - 2023 (USD Billion)
Table 39 Asia-Pacific Non-Invasive Prenatal Testing Market, By Application, 2025 - 2030 (USD Billion)
Table 40 Asia-Pacific Non-Invasive Prenatal Testing Market, By End User, 2018 - 2023 (USD Billion)
Table 41 Asia-Pacific Non-Invasive Prenatal Testing Market, By End User, 2025 - 2030 (USD Billion)
Table 42 Asia-Pacific Non-Invasive Prenatal Testing Market, By Region, 2018 - 2023 (USD Billion)
Table 43 Asia-Pacific Non-Invasive Prenatal Testing Market, By Region, 2025 - 2030 (USD Billion)
Table 44  RoW Non-Invasive Prenatal Testing Market, By Product, 2018 - 2023 (USD Billion)
Table 45  RoW Non-Invasive Prenatal Testing Market, By Product, 2025 - 2030 (USD Billion)
Table 46  RoW Non-Invasive Prenatal Testing Market, By Method, 2018 - 2023 (USD Billion)
Table 47  RoW Non-Invasive Prenatal Testing Market, By Method, 2025 - 2030 (USD Billion)
Table 48  RoW Non-Invasive Prenatal Testing Market, By Application, 2018 - 2023 (USD Billion)
Table 49  RoW Non-Invasive Prenatal Testing Market, By Application, 2025 - 2030 (USD Billion)
Table 50  RoW Non-Invasive Prenatal Testing Market, By End User, 2018 - 2023 (USD Billion)
Table 51  RoW Non-Invasive Prenatal Testing Market, By End User, 2025 - 2030 (USD Billion)
Table 52  RoW Non-Invasive Prenatal Testing Market, By Region, 2018 - 2023 (USD Billion)
Table 53  RoW Non-Invasive Prenatal Testing Market, By Region, 2025 - 2030 (USD Billion)
Table 54 Snapshot – GE Healthcare
Table 55 Snapshot – Perkinelmer Inc.
Table 56 Snapshot – Koninklijke N.V.
Table 57 Snapshot – Qiagen
Table 58 Snapshot – Pacific Biosciences of California Inc.
Table 59 Snapshot – Agilent Technologies Inc.
Table 60 Snapshot – Beijing Genomics Institute

List of Figures

Figure 1 Market Coverage
Figure 2 Research Phases
Figure 3 Secondary Sources for Different Parameters
Figure 4 Methodology
Figure 5 Data Mining & Exploration
Figure 6 Data Triangulation
Figure 7 Assumptions for Market Estimation and Forecast
Figure 8 Market Synopsis
Figure 9 Global Non-Invasive Prenatal Testing Market- Growth Drivers and Restraints
Figure 10 Competitive Benchmark
Figure 11 Global Non-Invasive Prenatal Testing Market Highlight
Figure 12 Global Non-Invasive Prenatal Testing Market, By Product, 2018 - 2030 (USD Billion)
Figure 13 Global Non-Invasive Prenatal Testing Market, By Method, 2018 - 2030 (USD Billion)
Figure 13 Global Non-Invasive Prenatal Testing Market, By Application, 2018 - 2030 (USD Billion)
Figure 14 Global Non-Invasive Prenatal Testing Market, By End User, 2018 - 2030 (USD Billion)
Figure 15 Global Non-Invasive Prenatal Testing Market, By Region, 2018 - 2030 (USD Billion)
Figure 16 North America Non-Invasive Prenatal Testing Market Highlight
Figure 17 North America Non-Invasive Prenatal Testing Market, By Product, 2018 - 2030 (USD Billion)
Figure 18 North America Non-Invasive Prenatal Testing Market, By Method, 2018 - 2030 (USD Billion)
Figure 18 North America Non-Invasive Prenatal Testing Market, By Application, 2018 - 2030 (USD Billion)
Figure 19 North America Non-Invasive Prenatal Testing Market, By End User, 2018 - 2030 (USD Billion)
Figure 20 North America Non-Invasive Prenatal Testing Market, by Region, 2018 - 2030 (USD Billion)
Figure 21 Europe Non-Invasive Prenatal Testing Market Highlight
Figure 22 Europe Non-Invasive Prenatal Testing Market, By Product, 2018 - 2030 (USD Billion)
Figure 23 Europe Non-Invasive Prenatal Testing Market, By Method, 2018 - 2030 (USD Billion)
Figure 23 Europe Non-Invasive Prenatal Testing Market, By Application, 2018 - 2030 (USD Billion)
Figure 24 Europe Non-Invasive Prenatal Testing Market, By End User, 2018 - 2030 (USD Billion)
Figure 25 Europe Non-Invasive Prenatal Testing Market, by Region, 2018 - 2030 (USD Billion)
Figure 26 Asia-Pacific Non-Invasive Prenatal Testing Market Highlight
Figure 27 Asia-Pacific Non-Invasive Prenatal Testing Market, By Product, 2018 - 2030 (USD Billion)
Figure 28 Asia-Pacific Non-Invasive Prenatal Testing Market, By Method, 2018 - 2030 (USD Billion)
Figure 28 Asia-Pacific Non-Invasive Prenatal Testing Market, By Application, 2018 - 2030 (USD Billion)
Figure 29 Asia-Pacific Non-Invasive Prenatal Testing Market, By End User, 2018 - 2030 (USD Billion)
Figure 30 Asia-Pacific Non-Invasive Prenatal Testing Market, by Region, 2018 - 2030 (USD Billion)
Figure 31 RoW Non-Invasive Prenatal Testing Market Highlight
Figure 32 RoW Non-Invasive Prenatal Testing Market, By Product, 2018 - 2030 (USD Billion)
Figure 33 RoW Non-Invasive Prenatal Testing Market, By Method, 2018 - 2030 (USD Billion)
Figure 33 RoW Non-Invasive Prenatal Testing Market, By Application, 2018 - 2030 (USD Billion)
Figure 34 RoW Non-Invasive Prenatal Testing Market, By End User, 2018 - 2030 (USD Billion)
Figure 35 RoW Non-Invasive Prenatal Testing Market, By Region, 2018 - 2030 (USD Billion)