Industry Overview
The Global Nucleic Acid Isolation and Purification Market was valued at USD 3.85 billion in 2023 and is anticipated to reach USD 7.9 billion, registering a CAGR of 9.2% during 2025-2030. Nucleic acid isolation and purification is molecular biology studies and recombinant DNA techniques. The process of isolation includes mechanical and chemical disruption and enzymatic digestion, whereas the purification involves electrophoresis, extraction, chromatography, affinity separation and centrifugation.
The global nucleic acid isolation and purification market is growing at significant rate, due to mounting public-private finance for life science research. Different product contributed to the nucleic acid isolation and purification market size. The market has witnessed high demand for kits over the last few years due to easiness of usage in applications such as gene cloning, gene sequencing, and molecular diagnostics.
Market Segmentation
Insight by Product
On the basis of product the market is subdivided into kits, instruments, and reagents. Of all product, kits segment accounted largest share in the market due to easiness of usage in applications such as gene cloning, gene sequencing, and molecular diagnostics, and less price. In addition, instruments segment is expected to grow at fastest rate in the market due to benefits of automated instruments.
Insight by Method
On the basis of method the market is subdivided into column-based, magnetic bead-based, reagent-based, and others. Quicker than organic extraction, cost-effective, and easier are the factors growing the demand of column-based. Among the all methods, the column-based accounted the largest share in the nucleic acid isolation and purification market. In addition, magnetic bead-based is expected to grow at fastest rate in the market due to upsurge throughput, and no use of hazardous chemicals.
Insight by Type
On the basis of type market is subdivided into messenger RNA, plasmid DNA, circulating nucleic acid, total RNA, microrna, PCR cleanup, genomic DNA and others. Among the all type, the plasmid DNA accounted the largest share in the nucleic acid isolation and purification market.
Insight by Application
On the basis of application the market is subdivided into precision medicine, diagnostics, agriculture and animal research, drug discovery & development and others. Mounting alertness of genomic diagnostics among the patient and escalating effectiveness of genomic sequencing in the analysis of diseases are the factors growing the demand of diagnostics application. Among the all applications, the diagnostics accounted the largest share and is expected to grow at fastest rate in the nucleic acid isolation and purification market.
Insight by End User
The different end user of the market are contract research organizations, academic and government research institutes, hospitals and diagnostic centers, pharmaceutical and biotechnology companies and other. The usage of nucleic acid tests in molecular diagnostics and mounting research activities are the factors growing the demand of nucleic acid isolation and purification in academic and government research institutes. Among the all end users, the academic and government research institutes accounted the largest share in the nucleic acid isolation and purification market.
Global Nucleic Acid Isolation and Purification Market Report Coverage
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Report Metric
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Details
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Historical Period
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2018 - 2023
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Base Year Considered
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2024
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Forecast Period
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2025 - 2030
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Market Size in 2023
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U.S.D. 3.85 Billion
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Revenue Forecast in 2030
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U.S.D. 7.9 Billion
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Growth Rate
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9.2%
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Segments Covered in the Report
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By Product, By Method, By Type, By Application, and By End-User
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Report Scope
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Market Trends, Drivers, and Restraints; Revenue Estimation and Forecast; Segmentation Analysis; Impact of COVID-19; Companies’ Strategic Developments; Market Share Analysis of Key Players; Company Profiling
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Regions Covered in the Report
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North America, Europe, Asia-Pacific, Middle East, and Rest of the World
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Industry Dynamics
Industry Trends
Personalized medicine and molecular diagnostics are the trends in the nucleic acid isolation and purification market.
Growth Drivers
The expanding automation, mounting public-private finance for life science research and technological improvement are the primary growth drivers for nucleic acid isolation and purification market.
In addition, mounting need of pure nucleic acids in pharmaceutical and biotechnological industries, escalating applications of these techniques in several fields such as molecular diagnostics, genetic engineering, forensics, and life science research and budding usage of nucleic acid-based tests in diagnosis are also up surging the growth in the market.
Challenges
The high cost of automated instruments and low market penetration for automated procedure are the major challenges for the growth of nucleic acid isolation and purification market.
Industry Ecosystem
Globally, the manufacturing companies trying to enter the nucleic acid isolation and purification market are required to maintain stringent regulatory standards. Moreover, the high level of capital requirement also poses a major barrier for the entry of new players. This offers an edge to the established players in the industry competition.
Geographic Overview
Geographically, North America is the largest nucleic acid isolation and purification market as in the region the government support is increasing. Major R&D expenditure in biotechnology and pharmaceutical companies, and technological improvements, are also up surging growth of the North American nucleic acid isolation and purification market.
Asia is observed to witness fastest growth in the market, due to promising government investments in the life sciences division. In addition, lesser manufacturing expenses and mounting occurrence of market players in emerging economies are also creating a positive impact on the nucleic acid isolation and purification market growth in the region.
Competitive Insight
Key players in the nucleic acid isolation and purification market are catering the demand of these devices by investing on technologically advanced products in their product portfolio across the globe. In May 2017, Thermo Fisher Scientific launched PureLink Expi Endotoxin-Free Maxi Plasmid Purification Kit, to improve its product portfolio of endotoxin-free plasmid DNA isolation products. Thermo Fisher Scientific, F. Hoffman-La Roche, Danaher Corporation, Qiagen N.V., Illumina, Agilent Technologies, Merck KGaA, Promega Corporation, Bio-Rad Laboratories and GE Healthcare are the key players offering nucleic acid isolation and purification.
The Nucleic Acid Isolation and Purification Market report offers a comprehensive market segmentation analysis along with an estimation for the forecast period 2025–2030.
Segments Covered in the Report
- By Product
- Kits
- Instruments
- Reagents
- By Method
- Column-Based
- Magnetic Bead-Based
- Reagent-Based
- Others
- By Type
- Messenger RNA
- Plasmid DNA
- Circulating Nucleic Acid
- Total RNA
- microRNA
- PCR Cleanup
- Genomic DNA
- Others
- By Application
- Precision Medicine
- Diagnostics
- Agriculture and Animal Research
- Drug Discovery & Development
- Others
- By End User
- Contract Research Organizations
- Academic and Government Research Institutes
- Hospitals and Diagnostic Centers
- Pharmaceutical and Biotechnology Companies
- Other
Region Covered in the Report
- North America
- Europe
- Germany
- U.K.
- France
- Italy
- Spain
- Russia
- Rest of Europe
- Asia-Pacific (APAC)
- China
- Japan
- India
- South Korea
- Rest of Asia-Pacific
- Rest of the World (RoW)
- Brazil
- Saudi Arabia
- South Africa
- U.A.E.
- Other Countries
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Source: VynZ Research
